Question

Lysosomes contain hydrolytic enzymes that derive from the endoplasmic reticulum (ER) and work best under a pH that is different from cytoplasmic pH. These enzymes, called lysozymes, use this low pH to degrade damaged macromolecules, but they are able to spare their own protein and enzyme contents.

Which of the following conditions is likely to cause a buildup of materials in the lysosome?

inhibiting the protein synthesis in the ER
decreasing the supply of amino acids to the cell by half
providing the cell with more nutrients so that more protein can be made
having a mutation in a lysosomal proteinase that renders it more resistant to self-digestion

Answer 1

D?

Step-by-step explanation:

Answer 2

The answer is D) having.a mutation in a lysosomal proteinase that renders it more resisitant to self-digestion.

Step-by-step explanation:

If the proteinase is more resisitant to the self-digestion, then the lyosome will have a build up of materials because the lysozymes now have a resistance and can survive besides their job, which causes the progressional increase of materials. This resistance basically is prohibiting the lyosome of doing its job.

Also, I took this on edge.