Question

The allosteric inhibitory effector BPG binds to both the A form and the F form. Both forms show a lower affinity for O2 in the presence of BPG. However, the inhibitory effect of BPG is larger for HbA. The different O2 affinity indicated by the curves has been attributed to different BPG affinity for the two Hb forms. Complete the statement.

BPG binds tighter to _____________ which ____________its affinity for O2.

Answer 1

HbA; lowers

Step-by-step explanation:

The BPG in our blood stands for Bisphosphoglyceric acid. It is known as by its name as 2,3-Bisphosphoglyceric acid. It is present in our blood in the red blood cells. It binds with more affinity towards the de-oxygenated hemoglobin as compared to the oxygenated hemoglobin.

Hemoglobin in blood delivers oxygen to our tissues moire efficiently. It is abbreviated as Hb.

Thus BPG binds more tightly towards HbA or adult hemoblobin and which lowers the affinity for oxygen.