A 76-year-old patient. Clinically present with anemia, thrombocytopenia and high white cell count. Hb 92 g/L, WBC 187 x10^9/L, platelet 37x10^9/L. Flow cytometry identified 80% of blasts. They are CD34-CD117+CD33+ cMPO+. Diagnosis? Describe the bone marrow changes?