Answer:
C.
If the line doesn't pass through the origin, the easiest point to pick is the origin (0,0). Substitute into your inequality.
y > 5x + 1
0 > 5(0) + 1
0 > 1 which is a false statement.
So, you shade the side of the line on which (0,0) doesn't lie.
If the statement would have be true, you shade the side of the line on which (0,0) lies.