Question

you have rebooted and scanned your system several times and it doesn't remove all malware. What is the next step?​

Answer 1

Reboot and scan one more time, then manually delete the infected files.

Answer 2

Revert, Reboot, Scan, and Re-scan

Step-by-step explanation:

If you've got System Restore points set in Windows, when malware attacks and can't be fixed, use this opportunity to reset the system. It could do the trick.but probably will not. The malware may be too smart.

You can reboot directly to Windows Defender Antivirus, the built-in antimalware tool that comes with Windows 10.