Answer:
49°
Explanation:
In the right triangle representing the sum of the various velocity vectors, the current represents the side opposite the angle, and the speed Debbie can swim represents the hypotenuse. The ratio Opposite/Hypotenuse is the sine of the angle, so we have ...
sin(α) = 3/4
α = arcsin(3/4) ≈ 48.6°
Debbie's swim direction needs to be about 49° upstream relative to the line she wants to follow.