Question

To answer this question, you may reference the Metabolic Map. The pentose phosphate pathway (PPP) is localized to the cytosol. Why is the localization of the PPP important? Reduced glutathione is formed using NADPH generated by the PPP. ATP production uses the NADPH generated by the PPP. Nucleotide synthesis uses the ribose 5‑phosphate generated by the PPP. Fatty acid β‑oxidation uses the FAD generated by the PPP. Fatty acid synthesis uses the NADPH generated by the PPP.

Answer 1

The pentose phosphate pathway (PPP) is found on the cytoplasm. The position of the [PPP] is useful for the following declarations:

Explanation:

• Fatty acid metabolism uses the PPP-generated NADPH.

• Nucleotide sequencing uses the 5-phosphate ribose produced by the PPP.

• Decreased collagen synthesis is produced using PPP-generated NADPH.

Since fatty acid metabolism, nucleic acid proliferation, and glutathione peroxidase sequencing from oxidized glutamate takes place is tied up, the product of PPP i.e. is basically needed during this process, the specificity of [PPP] is relevant in cytosols. NADPH, ribose 5-phosphate, or NADPH are readily available in cytosols as when the PPP is concentrated in cytosols.