Question

A researcher is working with a cell line that was derived from a tumor. The cells continuously divide in culture. The researcher transfected the cell line with a gene, and the cells stop dividing. The gene transfected into the cell line is a wild-type tumor _______ gene.

Answer 1

ANSWER: TUMOR SUPPRESSOR GENE

EXPLANATION: A cell line derived from a tumor will continue proliferates in culture.

However, a tumor suppressor gene (or sometimes referred to as anti-oncogene) is transfected to the cell line to inhibit continuous cell division and replication.

Furthermore, the likely category of tumor suppressor gene used is the gatekeeper genes, which directly regulate cell growth by either inhibiting cell cycle progression or inducing apoptosis (i.e a programmed cell death).

Answer 2

suppressor

Step-by-step explanation:

The gene transfected into the cell line is a wild-type tumor suppressor gene. Suppressor genes are involved in tumor formation when inactivated or lost, it regulates a cell during cell division and replication. The products of tumor suppressor genes inhibit cell division; the products of oncogenes increase cell division