Answer:
Topoisomerase
Step-by-step explanation:
Topoisomerase is an enzyme that is involved in the unwinding of Deoxyribonucleic acid (DNA). They are involved in double stranded DNA and they help to relieve the making of supercoils.
Topoisomerase play an important role during DNA replication, as the prevent the the twisting of the DNA double helix ahead of the replication fork. In other words, they ensure that the DNA open up for unwinding without being tightly wound.