Step-by-step explanation:
Frederick Griffith experimented on the Mice with the streptococcus pneumoniae strains. The virulent strain was called S strain smooth strain as it has a smooth layer whereas the avirulent strain was called the R strain or rough strain.
When he injected the virulent strain of bacteria by heat killing them and live R bacteria, he found that the mice were killed.
This shows that the live or avirulent bacteria became virulent or transformed into virulent bacteria by acquiring the virulent trait of the S bacteria. This led to the formation of the transforming principle.