Water is reduced by approximately 11/12.
Step-by-step explanation:
Concentration of blood = 300 mOsm
COncentration of urine = 3600 mOsm
Water loss = ?
Let x be the water loss
So,
The concentration is 3600 mOsm from 300 mOsm of blood
From 1 mOsm of urine = the concentration of blood is
mOsm

Negative sign indicates the loss.
water loss =

Therefore, the water loss is 11/12