Question

The steps in the process of endochondral ossification are a: Ossification center forms in the diaphysis b: Cartilage calcifies and a bone collar forms c: Ossification centers form in the epiphyses d: Bone replaces cartilage e: Epiphyseal plates ossify f: Cartilage model develops

Answer 1

Endochondral ossification is the process in which hyaline cartilage is converted into bone. It involves several steps, including the formation of ossification centers, calcification of cartilage, bone replacement, and ossification of the epiphyseal plates.

Step-by-step explanation:

Endochondral ossification is the process in which hyaline cartilage is converted into bone. It involves several steps:

1. Ossification center forms in the diaphysis: Mesenchymal cells differentiate into chondrocytes, and the cartilage model of the future bone begins to form.
2. Cartilage calcifies and a bone collar forms: Capillaries penetrate the cartilage, leading to the transformation of perichondrium into periosteum. The periosteal collar develops, and the primary ossification center forms.
3. Ossification centers form in the epiphyses: Secondary ossification centers develop in the regions of the epiphyses.
4. Bone replaces cartilage: Cartilage and chondrocytes continue to grow at the ends of the bone, and bone gradually replaces the cartilage.
5. Epiphyseal plates ossify: The hyaline cartilage at the epiphyseal plates ossifies, allowing bone lengthening.
6. Cartilage model develops: Cartilage remains at the epiphyseal (growth) plate and at the joint surface as articular cartilage.

Answer 2

During the development of the fetus, the mechanism by which the mammalian skeletal system gives rise to tissues of the bone is termed as endochondral ossification. Endochondral ossification also plays an essential role at the time of the development of the long bones length, rudimentary generation of the long bones, and healing of bone fractures naturally.

The following are the steps in the process of endochondral ossification:

f. The development of the cartilage model.

b. The calcification of cartilage takes place and the formation of bone collar occurs.

a. In the diaphysis, the formation of the ossification center takes place.

c. In the epiphysis, the formation of ossification centers takes place.

d. Replacement of cartilage takes place by the bone.

e. Ossification of epiphyseal plates takes place.