Question

Cyclosporine is a drug sometimes used to prevent transplant rejection after organ transplant surgery. This drug specifically disrupts cell-mediated immunity by cytotoxic T cells. Which of these events can be predicted based on this information?

Answer 1

Cyclosporine

Step-by-step explanation:

Antibody production will NOT be disrupted in the recipient in case of Cyclosporine

• Cyclosporine belongs to a class of drugs known as immunosuppressants,it works by slowing down body's defense system (immune system) to prevent the body from rejecting a transplanted organ
• Cyclosporine is used to prevent organ rejection in people who have received a liver, kidney, or heart transplant
• Cyclosporine is a neutral lipophilic polypeptide with an amino acid side chain,it is an immunomodulatory agent that belongs to the calcineurin inhibitors group and has a major effect in T cell activation
• Its major ability is to block the activation of the nuclear factor of activated T cells (NF-AT) required for transcription of cytokine genes namely the gene that encodes interleukin-2 (IL-2)
• IL-2 is a major enhancer for T-cell activation and recruitment