Question

DNA polymerase is a primer-dependent enzyme that functions only in the 5'-3' direction. These are the two most fundamental concepts to understanding this enzyme. Based on this, which of the following enzyme pairs are analogous in prokaryotes and eukaryotes?

1. DNA pol I : DNA pol α
2. DNA pol II : DNA pol β
3. DNA pol III : DNA pol δ4. All of the answers are correct

Answer 1

2. DNA polymerase II, DNA polymerase B

Step-by-step explanation:

DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA-Dependent DNA polymerase encoded by the PolB gene. DNA Polymerase II is an 89.9-kDa protein and is a member of the B family of DNA polymerases. The enzyme has 5′→3′ DNA synthesis capability as well as 3′→5′ exonuclease proofreading activity.

It was first isolated by Thomas Kornberg in 1970