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The transport of molecules of a particular solute from inside an animal cell across the cell membrane to the extracellular fluid always requires energy when ___

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When the concentration of the solute is lower inside the cell than outside it

--To pump a molecule across a membrane against its concentration gradient, the cell must expend metabolic energy, which is provided by ATP. This type of membrane traffic is called active transport.--
User Damian Walczak
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