Question

2‑Butanone is converted into 3‑methyl‑3‑hexanol using a Grignard reagent prepared from 1‑bromopropane and magnesium metal in THF solution. List the procedural steps required to collect the alcohol product by microdistillation.

Answer 1

1. Decant the THF solution into -25mL round-bottom flask

Step-by-step explanation:

1. Decant the THF solution into -25mL round-bottom flask.

2. Add boiling chips to the solution in round-bottom flask.

3. Grease all joints and attach the flask to a micro distillation apparatus.

4. Set apparatus in heating mantle and use heat shield tiles.

5. Adjust variac to distill THF at -60°C.

6. Increase variac setting to cause distillation of higher-boiling product.

7. Stop distillation before the flask becomes dry.