Question

Which of the following statements about 2,3-bisphosphoglycerate (BPG) binding is FALSE?

(A) BPG binds less tightly to fetal hemoglobin than to adult hemoglobin, thereby aiding oxygen transfer to a fetus.
(B) BPG binds to hemoglobin at one site and lowers hemoglobin's affinity for oxygen at another site.
(C) BPG aids oxygen delivery to tissues by increasing the affinity of myoglobin for oxygen.
(D) BPG requires a binding site containing multiple positively charged groups.

Answer 1

The answer is C: BPG aids oxygen delivery to tissues by increasing the affinity of myoglobin for oxygen.

Step-by-step explanation:

2,3-Bisphosphoglycerate (2,3-BPG) or BPG controls the affinity for haemoglobin to oxygen and not myoglobin. Myoglobin is a monomer, where as haemoglobin is a tetramer hence BPG cannot have an effect on myoglobin.