Final answer:
Constitutional isomers have different sequences of bonds, resulting in different chemical structures. Conformers are the result of rotational freedom around single bonds with the same chemical structure but different three-dimensional arrangements.
Step-by-step explanation:
Constitutional isomers, also known as structural isomers, have different sequences of bonds that result in different chemical structures. They can have different skeletal arrangements, functional groups, or positional arrangements. For example, butane and isobutane are constitutional isomers because they have the same molecular formula (C4H10) but different structures and properties.
On the other hand, conformers, also known as conformational isomers, are the result of rotation around single bonds. They have the same chemical structure but different three-dimensional arrangements due to rotational freedom. An example is ethane, where rotation around the carbon-carbon bond leads to different orientations of the hydrogen atoms.