The correct answer to this open question is the following.
Regarding farming, the best use of chemicals is a moderate one in order to not affect the crops. In big farming corporations, they use all kinds of pesticides to produce more crops because it's a business. But it is too much poison in fruits and vegetables that affects the nutrients of the food and could affect people when they consume these products. The farming industry is using pesticides, fungicides, insecticides, and more, to produce more food and trade it.
Natural pesticides are the best solution to cause less damage to plants and humans. More and more farmers are using organic pesticides although they are more expensive.