Answer:
There are several factors that can contribute to the effect an environmental toxin has on the human body. They are:
- Form and innate chemical activity
- Dosage, especially dose-time relationship
- Exposure route
- Species
- Life stage, such as infant, young adult, or elderly adult
- Gender
- Ability to be absorbed
- Metabolism
- Distribution within the body
- Excretion
- Health of the individual, including organ function and pregnancy, which involves physiological changes that could influence toxicity
- Nutritional status
- Presence of other chemicals
- Circadian rhythms (the time of day a drug or other substance is administered)