Answer:
basophils
Step-by-step explanation:
Basophils are a class of white blood cells known as granulocyte, which also include neutrophils, eosinophils, and mast cells. These cells (basophils) are generated in the bone marrow as other white blood cells. When stimulated, basophils degranulate to release histamine, proteoglycans, and proteolytic enzymes and thus mediate immune responses. This process of degranulation occurs when a specific antigen binds to the IgE receptor on the basophil. Moreover, basophils may also be activated by inflammatory mediators (e.g., complement factors such as C5a and C3a, chemokines, etc).