Answer:
Selective serotonin reuptake inhibitors (SSRIs)
Step-by-step explanation:
A synaptic cleft is a space that separates two neurons thereby forming a junction between two or more neurons. The synaptic cleft helps in the transfer of nerve impulse from one neuron to the other.
5-HT is found in the enteric nervous system located in the gastrointestinal tract and it helps in modulating cognition, memory, sleep, and numerous physiological processes.
Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine and citalopram are used to increase the level of 5-HT in the synaptic cleft by inhibiting its reuptake into the presynaptic terminal.