The correct answer to this open question is the following.
Although there are no options attached we can say the following.
“It will not be denied that power is of an encroaching nature and that it ought to be effectually restrained from passing the limits assigned to it.”
What James Madison meant when he said this quote was that power invades people's minds and creates ambition. Power sickens people, that is why power must be controlled and restrained because it is dangerous.
This idea was included by James Madison in Federalist Paper N.- 48, published on February 1, 1788.
The purpose of Alexander Hamilton, James Madison, and John Jay in writing The Federalist Papers was that they wanted to increase support for ratification of the Constitution.
The Federalists Papers were a series of articles written by Jong Jay, Alexander Hamilton, and James Madison under the pseudonym of "Publius," trying to get people to support the recently created US Constitution. Indeed, 85 articles were part of these Federalists Papers that rivaled with the Antifederalists Papers written by prominent politicians like Thomas Jefferson, who opposed the formation of a strong central government.