Final Answer:
The main or central idea of the passage is that British scientist Sir John Vane's research on the bothrops jararaca pit viper's venom led to the discovery of a mechanism to lower blood pressure, resulting in the development of widely used medications called ACE inhibitors.
Step-by-step explanation:
The passage discusses Sir John Vane's investigation into hypertension and his focus on the venom of the bothrops jararaca pit viper. The main idea revolves around Vane's hypothesis that understanding how the snake venom lowers blood pressure could lead to the development of medicines. The key discovery is that the venom blocks the production of angiotensin, a hormone that raises blood pressure, leading to the creation of ACE inhibitors. The central theme is the successful application of scientific research on snake venom to the development of medications for treating hypertension.