B. What level of interest are readers likely to have in my topic? would be the most appropriate question to ask yourself when considering how to address your audience for a procedural document.
This is because understanding your audience's level of interest in the topic can help you determine what level of detail to include in your document, what tone to use, and how to organize the information in a way that will be most useful and engaging for them. By considering your audience's needs and interests, you can create a document that will be more effective and easier to understand.