Answer:
Cytosine
Step-by-step explanation:
Cytosine contains the largest number of hydrogen bond acceptors when involved in a Watson-Crick base pair. Each of the four DNA bases - adenine, guanine, cytosine, and thymine - can form hydrogen bonds with their complementary base to form the building blocks of DNA.
However, cytosine has a larger number of hydrogen bond acceptors than the other bases, which makes it more prone to mutations and chemical damage, leading to various diseases.