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Which of the following accounts for the transition from membrane-bound IgM to secreted IgM upon activation of a B cell?A. CSRB. Affinity maturationC. Alternative splicing of pre-mRNAD. Additional modification
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Which of the following accounts for the transition from membrane-bound IgM to secreted IgM upon activation of a B cell?A. CSRB. Affinity maturationC. Alternative splicing of pre-mRNAD. Additional modification of nuclear DNA via RAG-1/2E. None of the above

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