Final answer:
The FDA is least concerned about the change in nutrient availability in food due to genetic engineering.
Step-by-step explanation:
The possible change in the composition of food that the FDA is least concerned about is the recombinant DNA might code for a protein that could change availability of nutrient levels in food because the protein may affect absorption or metabolism of nutrients. While this change can affect the nutrient levels in food, it is not considered a major concern because similar changes can occur through traditional breeding practices. The FDA's primary concerns lie in the introduction of allergens, directly toxic or allergenic recombinant DNA, and the modification of naturally occurring compounds to generate new toxic substances.