Final answer:
No tRNA corresponds to the termination codons (UAA, UAG, UGA) of mRNA; instead, release factors bind to the ribosome's A site, initiating the termination process of protein synthesis.
Step-by-step explanation:
Because there are no tRNAs with anticodons complementary to the termination codons of mRNA, no tRNA enters the A site of the ribosome when a termination codon is encountered; instead proteins called release factors bind to the ribosome. This occurs during the process of translation termination, where the ribosome encounters a stop codon (UAA, UAG, or UGA), leading to the binding of release factors that promote the release of the polypeptide chain and the disassembly of the translation machinery. The stop codons are also referred to as nonsense codons and are essential in marking the end of protein synthesis.