Question

Analysis of a post mortem Alzheimer's disease brain most likely will reveal the following characteristic changes compared to a normal brain from an individual of the similar age:

a. Narrowed gyri and widened sulci in the cortices and enlarged ventricles.
b. Massive loss of dopamine-releasing neurons in both the cortical and hippocampal regions.
c. Numerous amyloid plaques and neurofibrillary tangles both found inside the remaining neurons.
d. AandC.
e. A,B,andC.

Answer 1

A postmortem analysis of an Alzheimer's disease brain reveals narrowed gyri, widened sulci, enlarged ventricles, and the presence of amyloid plaques and neurofibrillary tangles, indicating the correct answer is d. AandC.

Step-by-step explanation:

Analysis of a postmortem Alzheimer's disease (AD) brain will most likely reveal the following characteristic changes compared to a normal brain of an individual of a similar age:

• Narrowed gyri and widened sulci in the cortices and enlarged ventricles.
• Amyloid plaques and neurofibrillary tangles both found inside the remaining neurons.

The correct answer is d. AandC, meaning narrowed gyri and widened sulci, enlarged ventricles, and the presence of amyloid plaques and neurofibrillary tangles are the characteristic changes found in the brains of patients with Alzheimer's disease.

Dopamine-releasing neuron loss is more associated with Parkinson's Disease, and thus option b. is not a consistent characteristic of Alzheimer's disease.