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The most common evidence for the existence of a genetic predisposition to autoimmune disease is in the higher incidence of the disease in monozygotic twins, with a lower but still increased incidence in dizygotic twins and family members when compared with an unrelated population. Although familial tendencies occur, the pattern of inheritance is complex and indicates that inheritance is?

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Anergic
Polygenic
Apoptotic
Tolerant

User Gareth Ma
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Final answer:

The most common evidence for the existence of a genetic predisposition to autoimmune disease is seen in the higher incidence of the disease in monozygotic twins. Inheritance of autoimmune diseases is complex and indicates polygenic inheritance.

Step-by-step explanation:

Evidence for the existence of a genetic predisposition to autoimmune disease is seen in the higher incidence of the disease in monozygotic twins, with a lower but still increased incidence in dizygotic twins and family members when compared with an unrelated population. This suggests that there is a genetic component to the development of autoimmune diseases.

Inheritance of autoimmune diseases is complex and indicates polygenic inheritance. This means that multiple genes are involved in contributing to the risk of developing autoimmune diseases.

It is important to note that while there is a genetic predisposition, environmental factors also play a role in triggering autoimmune diseases.

User Karthikeyan Ve
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