Question

The eosinophil is a terminally differentiated, end-stage leukocyte that resides predominantly in submucosal tissue and is recruited to sites of specific immune reactions, including allergic reactions. These cells settle in the tissue where their number is about 100 times higher than in the blood. In tissues and when activated, eosinophils release highly basic, preformed mediators such as eosinophil peroxidase. What else do they release?

Major basic protein
Granzymes
Bence Jones proteins
Caspases
Addresins

Answer 1

Activated eosinophils release several substances, with major basic protein being one of them, which is toxic to parasites and can damage host tissues.The correct option is A.

Step-by-step explanation:

The student's question pertains to what substances, besides eosinophil peroxidase, are released by activated eosinophils.

When eosinophils are activated, particularly during immune reactions like allergic responses, they release a variety of substances from their granules.

One such substance is major basic protein (MBP), which is known to be toxic to parasites and can also damage the tissues of the host.

Additionally, eosinophils release eosinophil-derived neurotoxin and eosinophil cationic protein, both of which have roles in combating parasitic infections and contributing to the damage caused during allergic reactions.The correct option is A.