Question

The expression of the immune response involves a certain amount of inflammation, cell infiltration, lymph node swelling, and even tissue destruction. Sometimes they are very severe. There are signs of an immune response in nearly all infections. Therefore, it is to be expected that there will nearly always be some contribution of the immune response to pathological changes. Sometimes this forms the major part of the disease. For example, in tuberculosis, much of the lung tissue damage is caused by the release of destructive enzymes by what?

Mast cells
Eosinophils
Dendritic cells
Basophils
Macrophages

Answer 1

In tuberculosis, much of the lung tissue damage is caused by the release of destructive enzymes by macrophages.

Step-by-step explanation:

In the context of tuberculosis and the resulting lung tissue damage, much of this damage is attributed to the release of destructive enzymes by macrophages. During an immune response, inflammation plays a crucial role, and macrophages are among the essential cells of the innate immune system that engage in eliminating pathogens.

They engulf and digest invading microbes, but in the process of fighting the infection, they can release enzymes and toxic products that inadvertently damage surrounding tissues. This is a double-edged sword of the immune system, where the response to protect the body can lead to pathological changes and contribute to the symptoms of a disease.