Question

Inhibition of the presynaptic voltage-sensitive Ca++ channels is most consistent with the presence of antibodies against which channel?

1) ACh receptor
2) presynaptic voltage-sensitive Ca++ channels
3) ryanodine receptor
4) residual ACh in the junction

Answer 1

The presence of antibodies against the presynaptic voltage-sensitive Ca++ channels can lead to their inhibition, affecting neurotransmitter release and synaptic transmission.

Step-by-step explanation:

The presence of antibodies against the presynaptic voltage-sensitive Ca++ channels can lead to their inhibition. In this scenario, the antibodies are targeting the voltage-sensitive Ca++ channels, preventing them from functioning properly. These channels are responsible for the influx of Ca++ ions into the presynaptic neuron, which triggers the release of neurotransmitters.

By inhibiting the voltage-sensitive Ca++ channels, the antibodies interfere with the normal process of neurotransmitter release and synaptic transmission. This disruption can have significant effects on neuronal communication and the function of the nervous system.

The correct answer to the question is 2) presynaptic voltage-sensitive Ca++ channels.