Final answer:
The Rhône River is the river that has the Saone, and Durance as tributaries, flowing through southeastern France and into the Mediterranean Sea.
Step-by-step explanation:
The river with the tributaries Saone, and Durance is the Rhône River. The Rhône is a major river in Europe, originating in the Swiss Alps and passing through Lake Geneva before running through southeastern France. The Saone is its longest tributary, joining the Rhône in Lyon, which is France's second largest city and a significant industrial center for modern technology. The Durance is another notable tributary, connecting to the Rhône in southern France. The Rhône ultimately empties into the Mediterranean Sea.