Question

PTHrP is similar to PTH but will differ in this function?

________. Function in regulating calcium levels
2) Function in bone development
3) Function in regulating phosphate levels
4) Function in muscle contraction

Answer 1

PTHrP differs from PTH in its primary function, which is bone development, not the regulation of calcium and phosphate levels that PTH is primarily associated with.

Step-by-step explanation:

PTHrP is similar to PTH (parathyroid hormone) but differs primarily in its function in bone development. While PTH regulates calcium levels by stimulating osteoclast proliferation, which releases calcium into the blood and promotes reabsorption of calcium by the kidney tubules, PTHrP plays a significant role in the development of cartilage and bone formation. Specifically, PTHrP regulates endochondral bone development, which is crucial during the formation of long bones in the fetus and during childhood growth.

Contrary to PTH, PTHrP does not significantly affect calcium levels in the same way. Although PTHrP can increase calcium levels in certain circumstances, its primary role in the body is the regulation of cartilage and bone development, distinguishing it from PTH in function.