Question

When patients are taking selective SSRIs for the first time for depression, which is most important to monitor for during the first few weeks of therapy?

Answer 1

During the first few weeks of therapy with selective serotonin reuptake inhibitors (SSRIs) for depression, it is important to monitor for side effects and worsening of symptoms.

Step-by-step explanation:

During the first few weeks of therapy with selective serotonin reuptake inhibitors (SSRIs) for depression, it is most important to monitor for side effects and worsening of symptoms. Common side effects of SSRIs include weight gain, fatigue, dizziness, loss of sexual desire, nausea, dry mouth, blurred vision, agitation, insomnia, and constipation. It is crucial to monitor for these side effects and consult with a healthcare professional if they become severe or concerning. In addition, SSRIs can initially worsen symptoms of depression before providing therapeutic effects. This is known as activation syndrome or stimulant effect. Patients may experience increased anxiety, restlessness, irritability, or insomnia at the beginning of treatment. Regular monitoring and communication with a healthcare professional is essential during this adjustment period.