Final answer:
Albumin concentration in blood plasma should be higher than globulin, with normal albumin levels being between 3.5 and 5.5 gms/100 ml and globulin levels are around 2-5 gms/dl. The albumin/globulin ratio is an important diagnostic tool, typically ranging from 1.2 to 1.8.
Step-by-step explanation:
In human blood plasma, the concentration of albumin should typically be higher than that of globulin. Albumin's concentration ranges from 3.5 to 5.5 gms/100 ml, making it the most abundant plasma protein. It plays a crucial role in maintaining osmotic pressure, transporting hormones and fatty acids, and buffering pH. In contrast, the concentration of globulins is about 2-5 gms/dl. These include alpha, beta, and gamma globulins, which are responsible for transporting various substances and are key components of the immune system.
The albumin/globulin ratio (A/G ratio) is an important indicator, generally ranging from 1.2 to 1.8, with an average of 1.5. An increased A/G ratio can indicate a decreased level of globulin, while a decreased A/G ratio may signify a reduced level of albumin. This ratio is crucial for diagnosing various conditions. For instance, in the central nervous system (CNS), an altered IgG index can suggest local CNS production of IgG or other conditions such as hypergammaglobulinemia or low serum albumin.