Final answer:
Drug therapy is generally recommended when LDL levels are above 160 mg/dL to reduce the risk of heart disease caused by high 'bad' cholesterol.
Step-by-step explanation:
Drug therapy should start when LDL levels are above 160 mg/dL. An LDL level of less than 100 mg/dL is considered ideal, while levels above this can contribute to atherosclerosis and an increased risk of heart disease. It is crucial to control LDL levels because they are a major factor in the buildup of plaque in your arteries, commonly referred to as 'bad' cholesterol. As one's LDL levels rise, particularly above the threshold of 160 mg/dL, the risk of heart attacks and other cardiovascular events likewise increases. Dietary modifications and increased physical activity are recommended to lower total cholesterol and improve the LDL:HDL ratio, both of which can help reduce the risk of heart disease without the need for drug therapy. However, if LDL levels remain high despite lifestyle changes, drug therapy may be necessary to mitigate health risks.