Final answer:
Prednisolone does not cause gingival enlargement, unlike Nifedipine, Cyclosporine, and Phenytoin, which are known to potentially cause this condition.
Step-by-step explanation:
The drug among the options provided that does NOT cause gingival enlargement is D. Prednisolone. Gingival enlargement is a side effect associated with certain medications. Nifedipine, Cyclosporine, and Phenytoin have all been known to potentially cause this condition. Prednisolone, a corticosteroid, is not commonly associated with gingival enlargement as a side effect. Healthcare professionals need to be aware of the gum changes that can occur with certain medications, so they can inform and monitor their patients accordingly.