Final answer:
Vasospastic angina is a chest pain caused by coronary artery spasms and may be triggered by certain negative inotropic drugs like some beta blockers and calcium channel blockers. Treatment typically involves nitroglycerin and other calcium channel blockers, statins, lifestyle changes, and potentially surgical interventions.
Step-by-step explanation:
Vasospastic angina, also known as Prinzmetal's angina, is a type of chest pain caused by spasms in the coronary arteries leading to reduced blood flow to the heart muscle. Certain drugs, such as negative inotropic agents including some beta blockers and calcium channel blockers, may be associated with triggering vasospastic episodes in susceptible individuals. These drugs are usually intended to decrease the strength of contraction of the heart and may precipitate vasospastic angina in some cases.
To treat vasospastic angina, lifestyle changes like smoking cessation and diet modification, along with medications, are recommended. Medications can include nitroglycerin, other specific calcium channel blockers that serve to prevent or relieve the spasms, and statins to reduce cholesterol levels. In some cases, surgical interventions such as angioplasty and stents may be necessary to improve blood flow.