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What is the MAC necessary to prevent laryngeal response to endotracheal intubation?

User BnMcGn
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Final answer:

The MAC necessary to suppress the laryngeal reflex during endotracheal intubation is dependent on the anesthetic used and patient factors, but must be sufficient to reach a deep level of anesthesia, generally above 1.0 MAC.

Step-by-step explanation:

The student is asking about the Minimum Alveolar Concentration (MAC) necessary to suppress a laryngeal reflex during an endotracheal intubation. MAC is a concept used in anesthesia to represent the potency of an anesthetic agent, defined as the concentration needed to prevent movement in response to a surgical stimulus in 50% of subjects. During intubation, an adequate level of anesthesia is important to prevent laryngeal and cough reflexes that could complicate the procedure.

In clinical practice, it is generally recommended that the anesthetic be dosed at a MAC level sufficient to blunt reflexes to intubation, which typically exceeds 1.0 MAC. The exact value can vary based on the anesthetic being used and patient-specific factors. The goal is to achieve a deep level of anesthesia to ensure patient safety and comfort. To prevent laryngeal response, most anesthesiologists will use a combination of potent anesthetics, muscle relaxants, and sometimes local anesthetics to sufficiently increase the depth of anesthesia and achieve appropriate conditions for intubation.

User Nael Marwan
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