Final answer:
The first line treatment for severe hypertriglyceridemia is dietary modification. If lifestyle changes are not enough, medications can be used to lower triglyceride levels. These may include statins, fibrates, and other agents.
Step-by-step explanation:
The first line treatment for severe hypertriglyceridemia, which carries a significant risk of pancreatitis, is dietary modification. This includes cutting back on calories and avoiding sugary and refined foods. If lifestyle changes are not enough, medications prescribed by a doctor can be used to lower triglyceride levels. These may include statins, fibrates, ezetimibe, niacin, bile acid sequestrants, and plant sterol-containing products and fatty acids.