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Injecting Botulinum toxin (Botox) directly into one or both vocal folds (thyroarytenoid muscles) has been used for which of the following voice conditions?

A. laryngeal webs
B. spasmodic dysphonia
C. carcinoma
D. polyps

User Bgporter
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Final answer:

Botulinum toxin, known as Botox, is used medically to reduce excessive muscle spasms in conditions such as spasmodic dysphonia by inhibiting acetylcholine release, which temporarily relaxes the vocal fold muscles.

Step-by-step explanation:

Botulinum toxin, often known by the brand name Botox, is a neurotoxin with various medical applications, including the treatment of disorders featuring excessive muscle contraction. One specific voice condition it is used for is spasmodic dysphonia, a condition characterized by involuntary spasms of the vocal cords that cause interruptions and changes in the voice. When Botox is carefully injected into the thyroarytenoid muscles of the vocal folds, it can reduce these muscle spasms, thereby improving voice quality and decreasing voice breaks for individuals diagnosed with spasmodic dysphonia.

The toxin accomplishes this therapeutically by inhibiting the release of acetylcholine from motor neurons, which in turn decreases muscle contractions. However, this effect is only temporary, requiring repeated injections to maintain vocal improvement. The use of Botox for treatments goes beyond cosmetic applications; it underscores a remarkable transformation of a potent toxin into a therapeutic agent for various conditions involving inappropriate nerve function and muscle contractions.

User Markus Kuhn
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