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Kidney stones, constipation/abd pain or psychiatric sxs, ↑[Ca], ↓[PO4], ↑vitD, ↑[PTH]? Dx? Txt?

User Openshac
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Final answer:

The patient's symptoms and lab values indicate primary hyperparathyroidism, causing calcium phosphate kidney stones. Treatment includes surgical management of the hyperparathyroidism and supportive measures for stone passage and prevention.

Step-by-step explanation:

The symptoms and lab findings described suggest a diagnosis of primary hyperparathyroidism (PHPT), which leads to the formation of calcium phosphate stones. The increased levels of calcium (hypercalcemia), decreased phosphate (hypophosphatemia), elevated vitamin D, and increased parathyroid hormone (PTH) seen in the labs confirm this. Other symptoms such as kidney stones, constipation, abdominal pain, and psychiatric symptoms like depression or confusion could also be associated with PHPT.

Treatment involves addressing the hyperparathyroidism, often through surgical removal of the overactive parathyroid gland(s). In the meantime, management of kidney stones may include increased fluid intake, dietary changes, and possibly medications like potassium citrate to prevent stone formation. In severe cases, lithotripsy or surgical removal of the stones may be necessary. Monitoring and managing blood calcium levels are also key components of treatment.

Renal colic and hematuria are common presenting symptoms of kidney stones, which occur when minerals crystallize in the urine due to metabolic disorders or dietary factors. The goal is to relieve pain, assist in the passage of the stone, and prevent new stone formation.

User Cyril Bvt
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