Question

This means DNA replication machinery cannot replicate sequence at the ? of the chromosomes, and after each round of DNA replication the ends of the chromosomes ?

Answer 1

Telomeres are the ends of linear chromosomes that cannot be replicated by the DNA replication machinery, resulting in their shortening with each round of replication.

Step-by-step explanation:

In eukaryotic chromosomes, the ends are known as telomeres. During DNA replication, the lagging strand, which is synthesized in short stretches, encounters a problem at the end of the linear chromosome. There is no place for a primer to be made for the DNA fragment to be copied at the end, so these ends remain unpaired and may get progressively shorter with each round of replication.