Final answer:
The V1 lead should be placed at the fourth intercostal space, right sternal border for accurate cardiac assessment.
Step-by-step explanation:
The proper location to place the V1 lead is at the fourth intercostal space, right sternal border. This is because when placing ECG leads for a 12-lead ECG, it is crucial to properly locate the leads relative to the structure of the heart and thorax. The V1 lead placement corresponds closely to the position of the heart within the thoracic cavity, specifically to the anterior surface near the right edge of the sternum. Correct placement ensures accurate readings for the assessment of cardiac physiology.