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According to AATB Standards, MS tissue donation is contraindicated when the donor has a history of any of the following EXCEPT:

a. Autoimmune disease
b. Malignancy
c. Active Tb
d. Rheumatoid arthritis

1 Answer

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Final answer:

According to AATB Standards, the history of autoimmune disease, malignancy, and active Tb are contraindications for tissue donation. However, rheumatoid arthritis is not generally considered an absolute contraindication for MS tissue donation.

Step-by-step explanation:

Contradictions for MS Tissue Donation

In the context of MS tissue donation according to AATB Standards, certain medical conditions can disqualify a potential donor from donating tissue due to the risks involved. Specifically, conditions such as autoimmune disease, malignancy, and active Tb (tuberculosis) are typically contraindicated because they can introduce significant risks to the recipient, such as infection or introducing malignant cells. However, rheumatoid arthritis, which is also an autoimmune disease, is generally not considered an absolute contraindication for tissue donation. Unlike some other autoimmune diseases, rheumatoid arthritis does not necessarily pose the same level of risk for the transmission of disease or complications in the recipient.

Overall, tissue transplantation requires careful consideration of the donor's and recipient's tissues to prevent rejection and ensure recipient safety. Transplant rejection occurs when the recipient's immune system attacks the donor tissue, which can be exacerbated by the presence of underlying medical conditions in the donor. While malignancy and active Tb are conditions that would typically prevent a person from being a tissue donor, rheumatoid arthritis is not listed as an exception in most standard tissue donation guidelines.

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