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How quickly can someone develop hyperCa from immobilization?

User Jeff Tsui
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Final answer:

Hypercalcemia can develop at different rates due to immobilization depending on various individual factors. It manifests as a high level of calcium in the blood which can disturb several body functions, regulated by hormones like PTH and vitamin D.

Step-by-step explanation:

The question asks how quickly someone can develop hyperCa (hypercalcemia) due to immobilization. Hypercalcemia is a medical condition where calcium levels in the blood are abnormally high. This condition can impact various bodily functions due to the critical role calcium plays in cell signaling, muscle contraction, and nerve function. Immobilization, such as being bedridden for an extended period, can lead to hypercalcemia because the lack of weight-bearing activity can result in calcium release from bones into the bloodstream. The onset of hypercalcemia from immobilization can vary depending on several factors like the extent of immobilization, underlying health conditions, and individual biological differences.

Hypercalcemia affects the nervous system, leading to symptoms like lethargy, sluggish reflexes, and in severe cases, confusion or coma. Also, issues like hyperparathyroidism could exacerbate the situation by causing an overproduction of parathyroid hormone (PTH) and increasing calcium reabsorption from bones. Maintaining a blood calcium level of about 10 mg/dL is crucial for normal body functions, and this balance is regulated by PTH, vitamin D, calcitonin, and interactions of various body systems including skeletal, endocrine, digestive, and urinary systems.