Final answer:
State regulatory powers regarding business are limited by Article I, Section 10, and several constitutional amendments, with key restrictions stemming from the Commerce Clause and the Necessary and Proper Clause.
Step-by-step explanation:
Limits are placed on a state's regulatory powers regarding business primarily by Article I, Section 10 of the U.S. Constitution. State powers are further restricted by a number of constitutional amendments, such as the Fourteenth Amendment and several civil rights amendments. Specifically, Article I, Section 10 prevents states from entering into treaties, coining money, and imposing duties on imports or exports. The Commerce Clause in Article I, Section 8, and the Necessary and Proper Clause are also interpreted to limit states' regulatory authority by granting Congress the power to regulate interstate commerce, which can supersede state legislation.